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Hironobu Minami Selected Research

NVP-AEW541

4/2013Mechanisms of acquired resistance to insulin-like growth factor 1 receptor inhibitor in MCF-7 breast cancer cell line.
9/2009Sensitivity of breast cancer cell lines to the novel insulin-like growth factor-1 receptor (IGF-1R) inhibitor NVP-AEW541 is dependent on the level of IRS-1 expression.

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Hironobu Minami Research Topics

Disease

107Neoplasms (Cancer)
10/2022 - 01/2002
23Breast Neoplasms (Breast Cancer)
03/2022 - 05/2005
13Neoplasm Metastasis (Metastasis)
04/2021 - 05/2005
11Disease Progression
12/2021 - 06/2005
11Neutropenia
01/2021 - 07/2004
9Diarrhea
01/2019 - 11/2006
8Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2019 - 01/2015
7Exanthema (Rash)
10/2022 - 07/2008
7Pancreatic Neoplasms (Pancreatic Cancer)
07/2022 - 04/2013
6Leukemia
03/2022 - 01/2011
6Melanoma (Melanoma, Malignant)
05/2021 - 05/2017
6Colorectal Neoplasms (Colorectal Cancer)
02/2021 - 10/2013
6Lymphoma (Lymphomas)
01/2021 - 10/2006
6Thyroid Neoplasms (Thyroid Cancer)
01/2021 - 01/2017
6Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
12/2020 - 07/2004
5Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
06/2022 - 02/2013
5Febrile Neutropenia
09/2021 - 02/2008
5Hypertension (High Blood Pressure)
01/2021 - 11/2006
5Nausea
01/2019 - 04/2009
5Stomach Neoplasms (Stomach Cancer)
01/2014 - 08/2012
4Infections
10/2022 - 05/2016
4COVID-19
04/2022 - 08/2021
4Head and Neck Neoplasms (Head and Neck Cancer)
09/2021 - 04/2009
4Pain (Aches)
04/2021 - 01/2014
4Anemia
12/2020 - 10/2006
4Fatigue
10/2016 - 10/2006
4Liver Diseases (Liver Disease)
10/2016 - 01/2009
3Biliary Tract Neoplasms (Biliary Tract Cancer)
07/2022 - 01/2015
3Heart Failure
03/2022 - 02/2013
3Multiple Myeloma
06/2021 - 05/2006
3Sarcoma (Soft Tissue Sarcoma)
04/2021 - 09/2019
3Left Ventricular Dysfunction
01/2021 - 08/2014
3Stomatitis
01/2020 - 04/2009
3Graft vs Host Disease (Graft-Versus-Host Disease)
02/2019 - 06/2011
3Hepatocellular Carcinoma (Hepatoma)
10/2016 - 03/2011
3Leukopenia
04/2009 - 06/2007
2Adenocarcinoma
07/2022 - 01/2014
2Triple Negative Breast Neoplasms
01/2022 - 05/2018
2Glioma (Gliomas)
12/2021 - 08/2017
2Carcinogenesis
02/2021 - 09/2020
2Cardiovascular Diseases (Cardiovascular Disease)
01/2021 - 01/2003

Drug/Important Bio-Agent (IBA)

15Irinotecan (Camptosar)FDA LinkGeneric
07/2022 - 01/2002
13Phosphotransferases (Kinase)IBA
06/2021 - 01/2007
12Pharmaceutical PreparationsIBA
02/2021 - 01/2002
11Biomarkers (Surrogate Marker)IBA
01/2022 - 04/2010
11Docetaxel (Taxotere)FDA Link
09/2021 - 07/2004
10NivolumabIBA
01/2022 - 05/2017
8Paclitaxel (Taxol)FDA LinkGeneric
10/2022 - 08/2006
8Cisplatin (Platino)FDA LinkGeneric
09/2021 - 07/2004
7Sorafenib (BAY 43-9006)FDA Link
12/2019 - 07/2008
6Messenger RNA (mRNA)IBA
04/2022 - 01/2013
6Proteins (Proteins, Gene)FDA Link
04/2022 - 03/2006
6lenvatinibIBA
01/2021 - 01/2017
6GemcitabineFDA Link
01/2021 - 06/2006
5LigandsIBA
01/2022 - 05/2006
5AnthracyclinesIBA
01/2021 - 12/2005
5Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2021 - 04/2010
5Tyrosine Kinase InhibitorsIBA
12/2019 - 01/2013
5MicroRNAs (MicroRNA)IBA
10/2019 - 12/2015
5Fluorouracil (Carac)FDA LinkGeneric
01/2014 - 12/2005
4ErbB Receptors (EGF Receptor)IBA
01/2022 - 03/2016
4Trastuzumab (Herceptin)FDA Link
01/2021 - 01/2007
4Carboplatin (JM8)FDA LinkGeneric
03/2019 - 06/2005
4CreatinineIBA
08/2017 - 02/2011
3blinatumomabIBA
06/2022 - 04/2020
3Immune Checkpoint InhibitorsIBA
04/2022 - 06/2017
3CytokinesIBA
10/2021 - 05/2017
3IodineIBA
01/2021 - 09/2018
3PlatinumIBA
01/2020 - 10/2006
3SteroidsIBA
09/2019 - 12/2015
3glasdegibIBA
06/2019 - 08/2017
3Mycophenolic Acid (Cellcept)FDA LinkGeneric
02/2019 - 06/2011
3Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2019 - 10/2010
3Hemoglobins (Hemoglobin)IBA
10/2016 - 10/2006
3AlbuminsIBA
01/2014 - 01/2005
3Antineoplastic Agents (Antineoplastics)IBA
01/2014 - 12/2005
3GSK 1363089IBA
10/2013 - 08/2012
3taxaneIBA
12/2012 - 12/2005
3Zoledronic Acid (Zometa)FDA Link
08/2011 - 01/2005
3Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA
04/2005 - 01/2002
2BNT162 VaccineIBA
04/2022 - 01/2022
2COVID-19 VaccinesIBA
04/2022 - 01/2022
2Immunoglobulin G (IgG)IBA
04/2022 - 05/2020
2Bevacizumab (Avastin)FDA Link
01/2022 - 10/2013
2AntibodiesIBA
11/2021 - 06/2008
2AdipokinesIBA
08/2021 - 01/2019
2Complement Factor D (Factor D)IBA
08/2021 - 01/2019
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2021 - 09/2009

Therapy/Procedure

40Therapeutics
06/2022 - 12/2005
29Drug Therapy (Chemotherapy)
04/2022 - 12/2003
6Drug Tapering
01/2019 - 06/2009
4Stem Cell Transplantation
03/2022 - 02/2013
4Hematopoietic Stem Cell Transplantation
01/2022 - 06/2011
4Radiotherapy
12/2021 - 02/2008
4Aftercare (After-Treatment)
12/2021 - 12/2015
4Chemoradiotherapy
01/2020 - 01/2011
3Bone Marrow Transplantation (Transplantation, Bone Marrow)
03/2019 - 01/2015
3Transplantation
02/2019 - 10/2015
2Immunotherapy
10/2021 - 08/2021
2Activities of Daily Living (ADL)
04/2021 - 10/2017